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Bacteria Transformation
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Students construct paper recombinant plasmids to simulate the methods genetic engineers use ...

Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role enzymes, DNA and genes play in the modification of organisms. For the particular model they work on, they isolate a mammal insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for production of the protein insulin.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Matthew Zelisko, Kimberly Anderson
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Date Added:
09/18/2014
The Benefits of Biodiversity
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Students toss coins to determine what traits a set of mouse parents ...

Students toss coins to determine what traits a set of mouse parents possess, such as fur color, body size, heat tolerance, and running speed. Then they use coin tossing to determine the traits a mouse pup born to these parents possesses. Then they compare these physical features to features that would be most adaptive in several different environmental conditions. Finally, students consider what would happen to the mouse offspring if those environmental conditions were to change: which mice would be most likely to survive and produce the next generation?

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Engineering K-PhD Program,
Mary R. Hebrank (project and lesson/activity consultant)
Date Added:
10/14/2015
Bioethics, Spring 2009
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" This course does not seek to provide answers to ethical questions. ...

" This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) ‰ŰÓ what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers."

Subject:
Fine Arts
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Hare, Caspar
Jones, David
Date Added:
01/01/2009
Chemicals in the Environment: Toxicology and Public Health (BE.104J), Spring 2005
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This course addresses the challenges of defining a relationship between exposure to ...

This course addresses the challenges of defining a relationship between exposure to environmental chemicals and human disease. Course topics include epidemiological approaches to understanding disease causation; biostatistical methods; evaluation of human exposure to chemicals, and their internal distribution, metabolism, reactions with cellular components, and biological effects; and qualitative and quantitative health risk assessment methods used in the U.S. as bases for regulatory decision-making. Throughout the term, students consider case studies of local and national interest.

Subject:
Environmental Science
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Sherley, James
Date Added:
01/01/2005
Cognitive and Behavioral Genetics, Spring 2001
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How genetics can add to our understanding of cognition, language, emotion, personality, ...

How genetics can add to our understanding of cognition, language, emotion, personality, and behavior. Use of gene mapping to estimate risk factors for psychological disorders and variation in behavioral and personality traits. Mendelian genetics, genetic mapping techniques, and statistical analysis of large populations and their application to particular studies in behavioral genetics. Topics also include environmental influence on genetic programs, evolutionary genetics, and the larger scientific, social, ethical, and philosophical implications.

Subject:
Biology
Genetics
Psychology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Nedivi, Elly
Pinker, Steve
Date Added:
01/01/2001
Computation for Biological Engineers, Fall 2006
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This course covers the analytical, graphical, and numerical methods supporting the analysis ...

This course covers the analytical, graphical, and numerical methods supporting the analysis and design of integrated biological systems. Topics include modularity and abstraction in biological systems, mathematical encoding of detailed physical problems, numerical methods for solving the dynamics of continuous and discrete chemical systems, statistics and probability in dynamic systems, applied local and global optimization, simple feedback and control analysis, statistics and probability in pattern recognition.

Subject:
Genetics
Statistics and Probability
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Alm, Eric
Date Added:
01/01/2006
DNA Build
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Students reinforce their knowledge that DNA is the genetic material for all ...

Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Denise W. Carlson
Integrated Teaching and Learning Program,
Janet Yowell
Malinda Schaefer Zarske
Megan Schroeder
Date Added:
09/18/2014
DNA Forensics and Color Pigments
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Students perform DNA forensics using food coloring to enhance their understanding of ...

Students perform DNA forensics using food coloring to enhance their understanding of DNA fingerprinting, restriction enzymes, genotyping and DNA gel electrophoresis. They place small drops of different food coloring ("water-based paint") on strips of filter paper and then place one paper strip end in water. As water travels along the paper strips, students observe the pigments that compose the paint decompose into their color components. This is an example of the chromatography concept applied to DNA forensics, with the pigments in the paint that define the color being analogous to DNA fragments of different lengths.

Subject:
Technology and Engineering
Life Science
Genetics
Physics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
TeachEngineering.org
Date Added:
09/18/2014
DNA: The Human Body Recipe
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As a class, students work through an example showing how DNA provides ...

As a class, students work through an example showing how DNA provides the "recipe" for making our body proteins. They see how the pattern of nucleotide bases (adenine, thymine, guanine, cytosine) forms the double helix ladder shape of DNA, and serves as the code for the steps required to make genes. They also learn some ways that engineers and scientists are applying their understanding of DNA in our world.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Lesson Plan
Teaching/Learning Strategy
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Denise W. Carlson
Frank Burkholder
Integrated Teaching and Learning Program,
Jessica Todd
Malinda Schaefer Zarske
Date Added:
09/18/2014
Design of Medical Devices and Implants, Spring 2006
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" This design course targets the solution of clinical problems by use ...

" This design course targets the solution of clinical problems by use of implants and other medical devices. Topics include the systematic use of cell-matrix control volumes; the role of stress analysis in the design process; anatomic fit, shape and size of implants; selection of biomaterials; instrumentation for surgical implantation procedures; preclinical testing for safety and efficacy, including risk/benefit ratio assessment evaluation of clinical performance and design of clinical trials. Student project materials are drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants."

Subject:
Health Science
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Spector, Myron
Yannas, Ioannis
Date Added:
01/01/2006
Don't Be a Square
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After watching video clips from the Harry Potter and the Goblet of ...

After watching video clips from the Harry Potter and the Goblet of Fire movie, students explore the use of Punnett squares to predict genetic trait inheritance. The objective of this lesson is to articulate concepts related to genetics through direct immersive interaction based on the theme, The Science Behind Harry Potter. Students' interest is piqued by the use of popular culture in the classroom.

Subject:
Technology and Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Christine Hawthorne
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Rachel Howser
Date Added:
09/18/2014
Dueling Mandates
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Using dilemma cards describing some of the issues affecting Yellowstone National Park, ...

Using dilemma cards describing some of the issues affecting Yellowstone National Park, students work in small groups to consider management issues that meet both of the conflicting mandates that the National Park Service must follow." There are 6 dilemmas that the class can be broken into groups to research. These dilemmas include wolf reintroduction, bison diseases, non-native trout, wildfires, resource sharing, and winter use of park lands. After researching each dilemma, students will make a pros/cons list, a final decision, and a brief presentation to the class. While the website recommends completing this lesson "after the expedition" to Yellowstone park, it can be done without visiting the park.

Subject:
Biology
Genetics
Material Type:
Lesson Plan
Provider:
California Foundation for Agriculture in the Classroom
National Science Teachers Association (NSTA)
Provider Set:
NGSS@NSTA
Date Added:
10/10/2017
Elements of Mechanical Design, Spring 2009
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" This is an advanced course on modeling, design, integration and best ...

" This is an advanced course on modeling, design, integration and best practices for use of machine elements such as bearings, springs, gears, cams and mechanisms. Modeling and analysis of these elements is based upon extensive application of physics, mathematics and core mechanical engineering principles (solid mechanics, fluid mechanics, manufacturing, estimation, computer simulation, etc.). These principles are reinforced via (1) hands-on laboratory experiences wherein students conduct experiments and disassemble machines and (2) a substantial design project wherein students model, design, fabricate and characterize a mechanical system that is relevant to a real world application. Students master the materials via problems sets that are directly related to, and coordinated with, the deliverables of their project. Student assessment is based upon mastery of the course materials and the student's ability to synthesize, model and fabricate a mechanical device subject to engineering constraints (e.g. cost and time/schedule)."

Subject:
Career and Technical Education
Technology and Engineering
Genetics
Chemistry
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Culpepper, Martin
Date Added:
01/01/2009
Engineering Nature: DNA Visualization and Manipulation
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Students are introduced to genetic techniques such as DNA electrophoresis and imaging ...

Students are introduced to genetic techniques such as DNA electrophoresis and imaging technologies used for molecular and DNA structure visualization. In the field of molecular biology and genetics, biomedical engineering plays an increasing role in the development of new medical treatments and discoveries. Engineering applications of nanotechnology such as lab-on-a-chip and deoxyribonucleic acid (DNA) microarrays are used to study the human genome and decode the complex interactions involved in genetic processes.

Subject:
Technology and Engineering
Life Science
Genetics
Physics
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
TeachEngineering.org
Date Added:
09/18/2014
Engineering Out of Harry Situations: The Science Behind Harry Potter
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Under the "The Science Behind Harry Potter" theme, a succession of diverse ...

Under the "The Science Behind Harry Potter" theme, a succession of diverse complex scientific topics are presented to students through direct immersive interaction. Student interest is piqued by the incorporation of popular culture into the classroom via a series of interactive, hands-on Harry Potter/movie-themed lessons and activities. They learn about the basics of acid/base chemistry (invisible ink), genetics and trait prediction (parseltongue trait in families), and force and projectile motion (motion of the thrown remembrall). In each lesson and activity, students are also made aware of the engineering connections to these fields of scientific study.

Subject:
Technology and Engineering
Life Science
Genetics
Mathematics
Chemistry
Physics
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Rachel Howser
TeachEngineering.org
Date Added:
09/18/2014
Evolving TCE Biodegraders
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A hypothetical scenario is introduced in which the class is asked to ...

A hypothetical scenario is introduced in which the class is asked to apply their understanding of the forces that drive natural selection to prepare a proposal along with an environmental consulting company to help clean up an area near their school that is contaminated with trichloroethylene (TCE). Students use the Avida-ED software application to test hypotheses for evolving (engineering) a strain of bacteria that can biodegrade TCE, resulting in a non-hazardous clean-up solution. Conduct this design challenge activity after completion of the introduction to digital evolution activity, Studying Evolution with Digital Organisms.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Amy Lark
Bio-Inspired Technology and Systems (BITS) RET,
Louise Mead
Robert Pennock
Wendy Johnson
Date Added:
09/18/2014
Experimental Microbial Genetics, Fall 2008
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" In this class, students engage in independent research projects to probe ...

" In this class, students engage in independent research projects to probe various aspects of the physiology of the bacteriumĺĘPseudomonas aeruginosa PA14, an opportunistic pathogen isolated from the lungs of cystic fibrosis patients. Students use molecular genetics to examine survival in stationary phase, antibiotic resistance, phase variation, toxin production, and secondary metabolite production. Projects aim to discover the molecular basis for these processes using both classical and cutting-edge techniques. These include plasmid manipulation, genetic complementation, mutagenesis, PCR, DNA sequencing, enzyme assays, and gene expression studies. Instruction and practice in written and oral communication are also emphasized. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented. Legal Notice "

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Croal, Laura
Laub, Michael
Melvold, Janis
Newman, Dianne
Date Added:
01/01/2008
A Family in Need: In-Class Case Study on Cancer Genetics
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“A Family in Need” was designed as an in-class problem-based learning activity ...

“A Family in Need” was designed as an in-class problem-based learning activity for students to learn about several innovative medical applications of molecular biology. Students assume the role of a second-year medical student assigned to work with a pediatric oncologist who has just biopsied a tumor-like growth in the adrenal gland of her 17-year-old patient, Lee F. After taking Lee’s family history and performing a pedigree analysis, students review clinical and genetic characteristics of several syndromes associated with adrenal cancer. Students then explore various diagnostic and biomedical research techniques such as PCR, DNA sequencing, and pre-implantation genetic diagnosis. The case concludes with a consideration of how to treat Lee’s condition with the help of gene cloning and the potential of gene therapy. Although originally written for an upper-level college genetics course, the case could also be adapted for an introductory molecular/cellular biology course, a non-majors biology course, or a professional school medical genetics course.

Subject:
Genetics
Material Type:
Case Study
Lecture Notes
Unit of Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Date Added:
11/09/2017
The Fountain of Life: From Dolly to Customized Embryonic Stem Cells, Fall 2007
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" During development, the genetic content of each cell remains, with a ...

" During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimentally proven. Only 10 years ago the sheep Dolly was the first mammal to be cloned from an adult organism, demonstrating that the differentiated state of a mammalian cell can be fully reversible to a pluripotent embryonic state. A key conclusion from these experiments was that the difference between pluripotent cells such as embryonic stem (ES) cells and unipotent differentiated cells is solely a consequence of reversible changes. These changes, which have proved to involve reversible alterations to both DNA and to proteins that bind DNA, are known as epigenetic, to distinguish them from genetic alterations to DNA sequence. In this course we will explore such epigenetic changes and study different approaches that can return a differentiated cell to an embryonic state in a process referred to as epigenetic reprogramming, which will ultimately allow generation of patient-specific stem cells and application to regenerative therapy. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching."

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Meissner, Alexander
Date Added:
01/01/2007
Freshman Seminar: Structural Basis of Genetic Material: Nucleic Acids, Fall 2005
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Since the discovery of the structure of the DNA double helix in ...

Since the discovery of the structure of the DNA double helix in 1953 by Watson and Crick, the information on detailed molecular structures of DNA and RNA, namely, the foundation of genetic material, has expanded rapidly. This discovery is the beginning of the "Big Bang" of molecular biology and biotechnology. In this seminar, students discuss, from a historical perspective and current developments, the importance of pursuing the detailed structural basis of genetic materials.

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Zhang, Shuguang
Date Added:
01/01/2005
Gene Expression - The Basics
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Express yourself through your genes! See if you can generate and collect ...

Express yourself through your genes! See if you can generate and collect three types of protein, then move on to explore the factors that affect protein synthesis in a cell.

Subject:
Genetics
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Ariel Paul
George Emanuel
John Blanco
Kathy Perkins
Mike Klymkowsky
PhET Interactive Simulations
Tom Perkins
Date Added:
08/20/2012
Gene Machine: The Lac Operon
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Build a gene network! The lac operon is a set of genes ...

Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Genetics
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Blanco, John
George Spiegelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Perkins, Kathy
PhET Interactive Simulations
Podolefsky, Noah
Speigelman, George
Taylor, Jared
Date Added:
05/01/2010
Gene Machine: The Lac Operon (AR)
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Build a gene network! The lac operon is a set of genes ...

Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Genetics
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Blanco, John
Perkins, Kathy
Podolefsky, Noah
Speigelman, George
Taylor, Jared
Date Added:
05/01/2010
General Biology I
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An integrated course stressing the principles of biology. Life processes are examined ...

An integrated course stressing the principles of biology. Life processes are examined primarily at the molecular and cellular levels. Intended for students majoring in biology or for non-majors who wish to take advanced biology courses.

Subject:
Biology
Genetics
Chemistry
Material Type:
Activity/Lab
Full Course
Lecture Notes
Syllabus
Provider:
UMass Boston
Provider Set:
UMass Boston OpenCourseWare
Author:
Ph.D.
Professor Brian White
Date Added:
11/09/2017
Genetic Neurobiology, Fall 2005
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Deals with the specific functions of neurons, the interactions of neurons in ...

Deals with the specific functions of neurons, the interactions of neurons in development, and the organization of neuronal ensembles to produce behavior, by functional analysis of mutations and molecular analysis of their genes. Concentrates on work with nematodes, fruit flies, mice, and humans.

Subject:
Biology
Genetics
Psychology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Littleton, Troy
Quinn, William
Date Added:
01/01/2005
Geneticist Pardis Sabeti
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In this video profile adapted from NOVA scienceNOW, learn about geneticist and ...

In this video profile adapted from NOVA scienceNOW, learn about geneticist and rock musician Pardis Sabeti, whose innovative insights into natural selection demonstrated how beneficial mutations spread quickly through a population.

Subject:
Life Science
Genetics
Material Type:
Lecture
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media Common Core Collection
Teachers' Domain
Author:
Alfred P. Sloan Foundation
HHMI
National Science Foundation
Public Television Viewers
WGBH Educational Foundation
Date Added:
08/20/2008
Genetics Case Studies
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Wrestle with ethical issues concerning genetic rights and practices from the NOVA: ...

Wrestle with ethical issues concerning genetic rights and practices from the NOVA: "Cracking the Code of Life" Web site.

***Access to Teacher's Domain content now requires free login to PBS Learning Media.

Subject:
Genetics
Material Type:
Activity/Lab
Case Study
Provider:
PBS LearningMedia
Provider Set:
WGBH Educational Foundation
Author:
WGBH Educational Foundation
Date Added:
09/26/2003
Genomic Medicine, Spring 2004
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This course reviews the key genomic technologies and computational approaches that are ...

This course reviews the key genomic technologies and computational approaches that are driving advances in prognostics, diagnostics, and treatment. Throughout the semester, emphasis will return to issues surrounding the context of genomics in medicine including: what does a physician need to know? what sorts of questions will s/he likely encounter from patients? how should s/he respond? Lecturers will guide the student through real world patient-doctor interactions. Outcome considerations and socioeconomic implications of personalized medicine are also discussed. The first part of the course introduces key basic concepts of molecular biology, computational biology, and genomics. Continuing in the informatics applications portion of the course, lecturers begin each lecture block with a scenario, in order to set the stage and engage the student by showing: why is this important to know? how will the information presented be brought to bear on medical practice? The final section presents the ethical, legal, and social issues surrounding genomic medicine. A vision of how genomic medicine relates to preventative care and public health is presented in a discussion forum with the students where the following questions are explored: what is your level of preparedness now? what challenges must be met by the healthcare industry to get to where it needs to be?

Subject:
Health Science
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Kohane, Isaac
Date Added:
01/01/2004
Heredity
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This module is a complete set of lessons "How do the differences ...

This module is a complete set of lessons "How do the differences arise in DNA that leads to differences in characteristics. Teacher module overview video included. Focus on the origin of genetic variation and how it gives rise to diverse traits. Each exercise has guiding questions. Modules include worksheets, videos, the time needed for each section, links to other resources, assessment.

Subject:
Genetics
Material Type:
Activity/Lab
Assessment
Homework/Assignment
Learning Task
Author:
Teach Genetics
Date Added:
12/12/2018
Heredity Mix n Match
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Students randomly select jelly beans (or other candy) that represent genes for ...

Students randomly select jelly beans (or other candy) that represent genes for several human traits such as tongue-rolling ability and eye color. Then, working in pairs (preferably of mixed gender), students randomly choose new pairs of jelly beans from those corresponding to their own genotypes. The new pairs are placed on toothpicks to represent the chromosomes of the couple's offspring. Finally, students compare genotypes and phenotypes of parents and offspring for all the "couples" in the class. In particular, they look to see if there are cases where parents and offspring share the exact same genotype and/or phenotype, and consider how the results would differ if they repeated the simulation using more than four traits.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Mary R. Hebrank
Date Added:
09/26/2008
Imaging DNA Structure
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Students are introduced to the latest imaging methods used to visualize molecular ...

Students are introduced to the latest imaging methods used to visualize molecular structures and the method of electrophoresis that is used to identify and compare genetic code (DNA). Students should already have basic knowledge of genetics, DNA (DNA structure, nucleotide bases), proteins and enzymes. The lesson begins with a discussion to motivate the need for imaging techniques and DNA analysis, which prepares students to participate in the associated two-part activity: 1) students each choose an imaging method to research (from a provided list of molecular imaging methods), 2) they research basic information about electrophoresis.

Subject:
Technology and Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Mircea Ionescu
Myla Van Duyn
University of Houston,
Date Added:
09/18/2014
Inside the DNA
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Students conduct their own research to discover and understand the methods designed ...

Students conduct their own research to discover and understand the methods designed by engineers and used by scientists to analyze or validate the molecular structure of DNA, proteins and enzymes, as well as basic information about gel electrophoresis and DNA identification. In this computer-based activity, students investigate particular molecular imaging technologies, such as x-ray, atomic force microscopy, transmission electron microscopy, and create short PowerPoint presentations that address key points. The presentations include their own explanations of the difference between molecular imaging and gel electrophoresis.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Mircea Ionescu
Myla Van Duyn
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Date Added:
09/18/2014
Introduction to Biological Engineering Design, Spring 2009
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" This class is a project-based introduction to the engineering of synthetic ...

" This class is a project-based introduction to the engineering of synthetic biological systems. Throughout the term, students develop projects that are responsive to real-world problems of their choosing, and whose solutions depend on biological technologies. Lectures, discussions, and studio exercises will introduce (1) components and control of prokaryotic and eukaryotic behavior, (2) DNA synthesis, standards, and abstraction in biological engineering, and (3) issues of human practice, including biological safety; security; ownership, sharing, and innovation; and ethics. Enrollment preference is given to freshmen. This subject was originally developed and first taught in Spring 2008 by Drew Endy and Natalie Kuldell. Many of Drew's materials are used in this Spring 2009 version, and are included with his permission. This OCW Web site is based on the OpenWetWare class Wiki, found at OpenWetWare: 20.020 (S09)"

Subject:
Biology
Genetics
Chemistry
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Kuldell, Natalie
Date Added:
01/01/2009
Introduction to Evolutionary Computation
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Students are introduced to the concepts of evolution by natural selection and ...

Students are introduced to the concepts of evolution by natural selection and digital evolution software. They learn about the field of evolutionary computation, which applies the principles of natural selection to solve engineering design problems. They learn the similarities and differences between natural selection and the engineering design process.

Subject:
Technology and Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Bio-Inspired Technology and Systems (BITS) RET,
Wendy Johnson
Date Added:
09/18/2014
Introduction to Genetic Engineering and Its Applications
Conditions of Use:
Read the Fine Print
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Students learn how engineers apply their understanding of DNA to manipulate specific ...

Students learn how engineers apply their understanding of DNA to manipulate specific genes to produce desired traits, and how engineers have used this practice to address current problems facing humanity. They learn what genetic engineering means and examples of its applications, as well as moral and ethical problems related to its implementation. Students fill out a flow chart to list the methods to modify genes to create GMOs and example applications of bacteria, plant and animal GMOs.

Subject:
Technology and Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Matthew Zelisko, Kimberly Anderson
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Date Added:
09/18/2014
Let's Make Silly Putty
Conditions of Use:
Read the Fine Print
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Students make two different formulations of imitation Silly Putty with varying degrees ...

Students make two different formulations of imitation Silly Putty with varying degrees of cross-linking. They witness how changes in the degree of cross-linking influence the putty properties.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Cherelle M. Bishop
CHIP GK-12 Project,
Jeramy Jasmann
Kate McDonnell
Melissa M. Reynolds
Michael A. de Miranda
Date Added:
09/18/2014
Mice Rule! (Or Not)
Conditions of Use:
Read the Fine Print
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Students explore the relationships between genetics, biodiversity, and evolution through a simple ...

Students explore the relationships between genetics, biodiversity, and evolution through a simple activity involving hypothetical wild mouse populations. First, students toss coins to determine what traits a set of mouse parents possesses, such as fur color, body size, heat tolerance, and running speed. Next they use coin tossing to determine the traits a mouse pup born to these parents possesses. These physical features are then compared to features that would be most adaptive in several different environmental conditions. Finally, students consider what would happen to the mouse offspring if those environmental conditions were to change: which mice would be most likely to survive and produce the next generation?

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Engineering K-PhD Program,
Mary R. Hebrank (project and lesson/activity consultant)
Date Added:
09/18/2014
Molecular Biology and Genetics in Modern Medicine, Fall 2007
Conditions of Use:
Remix and Share
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" This course provides a foundation for understanding the relationship between molecular ...

" This course provides a foundation for understanding the relationship between molecular biology, developmental biology, genetics, genomics, bioinformatics, and medicine. It develops explicit connections between basic research, medical understanding, and the perspective of patients. Principles of human genetics are reviewed. We translate clinical understanding into analysis at the level of the gene, chromosome and molecule; we cover the concepts and techniques of molecular biology and genomics, and the strategies and methods of genetic analysis, including an introduction to bioinformatics. Material in the course extends beyond basic principles to current research activity in human genetics."

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Giersch, Anne
Housman, David
Date Added:
01/01/2007
Molecular Motors
Conditions of Use:
Read the Fine Print
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Discover what controls how fast tiny molecular motors in our body pull ...

Discover what controls how fast tiny molecular motors in our body pull through a single strand of DNA. How hard can the motor pull in a tug of war with the optical tweezers? Discover what helps it pull harder. Do all molecular motors behave the same?

Subject:
Genetics
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Adams, Wendy
Betterton, Meredith
Chris Malley
Dubson, Mike
Kathy Perkins
Malley, Chris
Meredith Betterton
Mike Dubson
Perkins, Kathy
Perkins, Tom
PhET Interactive Simulations
Tom Perkins
Wendy Adams
Date Added:
12/01/2007