Search Results (62)

View
Selected filters:
  • Genetics
Bacteria Transformation
Read the Fine Print
Educational Use
Rating

Students construct paper recombinant plasmids to simulate the methods genetic engineers use ...

Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role enzymes, DNA and genes play in the modification of organisms. For the particular model they work on, they isolate a mammal insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for production of the protein insulin.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Matthew Zelisko, Kimberly Anderson
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Date Added:
09/18/2014
The Benefits of Biodiversity
Read the Fine Print
Educational Use
Rating

Students toss coins to determine what traits a set of mouse parents ...

Students toss coins to determine what traits a set of mouse parents possess, such as fur color, body size, heat tolerance, and running speed. Then they use coin tossing to determine the traits a mouse pup born to these parents possesses. Then they compare these physical features to features that would be most adaptive in several different environmental conditions. Finally, students consider what would happen to the mouse offspring if those environmental conditions were to change: which mice would be most likely to survive and produce the next generation?

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Engineering K-PhD Program,
Mary R. Hebrank (project and lesson/activity consultant)
Date Added:
10/14/2015
Bioethics, Spring 2009
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating

" This course does not seek to provide answers to ethical questions. ...

" This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) ‰ŰÓ what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers."

Subject:
Fine Arts
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Hare, Caspar
Jones, David
Date Added:
01/01/2009
Chemicals in the Environment: Toxicology and Public Health (BE.104J), Spring 2005
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating

This course addresses the challenges of defining a relationship between exposure to ...

This course addresses the challenges of defining a relationship between exposure to environmental chemicals and human disease. Course topics include epidemiological approaches to understanding disease causation; biostatistical methods; evaluation of human exposure to chemicals, and their internal distribution, metabolism, reactions with cellular components, and biological effects; and qualitative and quantitative health risk assessment methods used in the U.S. as bases for regulatory decision-making. Throughout the term, students consider case studies of local and national interest.

Subject:
Environmental Science
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Sherley, James
Date Added:
01/01/2005
Cognitive and Behavioral Genetics, Spring 2001
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating

How genetics can add to our understanding of cognition, language, emotion, personality, ...

How genetics can add to our understanding of cognition, language, emotion, personality, and behavior. Use of gene mapping to estimate risk factors for psychological disorders and variation in behavioral and personality traits. Mendelian genetics, genetic mapping techniques, and statistical analysis of large populations and their application to particular studies in behavioral genetics. Topics also include environmental influence on genetic programs, evolutionary genetics, and the larger scientific, social, ethical, and philosophical implications.

Subject:
Biology
Genetics
Psychology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Nedivi, Elly
Pinker, Steve
Date Added:
01/01/2001
Computation for Biological Engineers, Fall 2006
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating

This course covers the analytical, graphical, and numerical methods supporting the analysis ...

This course covers the analytical, graphical, and numerical methods supporting the analysis and design of integrated biological systems. Topics include modularity and abstraction in biological systems, mathematical encoding of detailed physical problems, numerical methods for solving the dynamics of continuous and discrete chemical systems, statistics and probability in dynamic systems, applied local and global optimization, simple feedback and control analysis, statistics and probability in pattern recognition.

Subject:
Genetics
Statistics and Probability
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Alm, Eric
Date Added:
01/01/2006
DNA Build
Read the Fine Print
Educational Use
Rating

Students reinforce their knowledge that DNA is the genetic material for all ...

Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Denise W. Carlson
Integrated Teaching and Learning Program,
Janet Yowell
Malinda Schaefer Zarske
Megan Schroeder
Date Added:
09/18/2014
DNA Forensics and Color Pigments
Read the Fine Print
Educational Use
Rating

Students perform DNA forensics using food coloring to enhance their understanding of ...

Students perform DNA forensics using food coloring to enhance their understanding of DNA fingerprinting, restriction enzymes, genotyping and DNA gel electrophoresis. They place small drops of different food coloring ("water-based paint") on strips of filter paper and then place one paper strip end in water. As water travels along the paper strips, students observe the pigments that compose the paint decompose into their color components. This is an example of the chromatography concept applied to DNA forensics, with the pigments in the paint that define the color being analogous to DNA fragments of different lengths.

Subject:
Technology and Engineering
Life Science
Genetics
Physics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
TeachEngineering.org
Date Added:
09/18/2014
DNA: The Human Body Recipe
Read the Fine Print
Educational Use
Rating

As a class, students work through an example showing how DNA provides ...

As a class, students work through an example showing how DNA provides the "recipe" for making our body proteins. They see how the pattern of nucleotide bases (adenine, thymine, guanine, cytosine) forms the double helix ladder shape of DNA, and serves as the code for the steps required to make genes. They also learn some ways that engineers and scientists are applying their understanding of DNA in our world.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Lesson Plan
Teaching/Learning Strategy
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Denise W. Carlson
Frank Burkholder
Integrated Teaching and Learning Program,
Jessica Todd
Malinda Schaefer Zarske
Date Added:
09/18/2014
Design of Medical Devices and Implants, Spring 2006
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating

" This design course targets the solution of clinical problems by use ...

" This design course targets the solution of clinical problems by use of implants and other medical devices. Topics include the systematic use of cell-matrix control volumes; the role of stress analysis in the design process; anatomic fit, shape and size of implants; selection of biomaterials; instrumentation for surgical implantation procedures; preclinical testing for safety and efficacy, including risk/benefit ratio assessment evaluation of clinical performance and design of clinical trials. Student project materials are drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants."

Subject:
Health Science
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Spector, Myron
Yannas, Ioannis
Date Added:
01/01/2006
Don't Be a Square
Read the Fine Print
Educational Use
Rating

After watching video clips from the Harry Potter and the Goblet of ...

After watching video clips from the Harry Potter and the Goblet of Fire movie, students explore the use of Punnett squares to predict genetic trait inheritance. The objective of this lesson is to articulate concepts related to genetics through direct immersive interaction based on the theme, The Science Behind Harry Potter. Students' interest is piqued by the use of popular culture in the classroom.

Subject:
Technology and Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Christine Hawthorne
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Rachel Howser
Date Added:
09/18/2014
Dueling Mandates
Rating

Using dilemma cards describing some of the issues affecting Yellowstone National Park, ...

Using dilemma cards describing some of the issues affecting Yellowstone National Park, students work in small groups to consider management issues that meet both of the conflicting mandates that the National Park Service must follow." There are 6 dilemmas that the class can be broken into groups to research. These dilemmas include wolf reintroduction, bison diseases, non-native trout, wildfires, resource sharing, and winter use of park lands. After researching each dilemma, students will make a pros/cons list, a final decision, and a brief presentation to the class. While the website recommends completing this lesson "after the expedition" to Yellowstone park, it can be done without visiting the park.

Subject:
Biology
Genetics
Material Type:
Lesson Plan
Provider:
California Foundation for Agriculture in the Classroom
National Science Teachers Association (NSTA)
Provider Set:
NGSS@NSTA
Date Added:
10/10/2017
Elements of Mechanical Design, Spring 2009
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating

" This is an advanced course on modeling, design, integration and best ...

" This is an advanced course on modeling, design, integration and best practices for use of machine elements such as bearings, springs, gears, cams and mechanisms. Modeling and analysis of these elements is based upon extensive application of physics, mathematics and core mechanical engineering principles (solid mechanics, fluid mechanics, manufacturing, estimation, computer simulation, etc.). These principles are reinforced via (1) hands-on laboratory experiences wherein students conduct experiments and disassemble machines and (2) a substantial design project wherein students model, design, fabricate and characterize a mechanical system that is relevant to a real world application. Students master the materials via problems sets that are directly related to, and coordinated with, the deliverables of their project. Student assessment is based upon mastery of the course materials and the student's ability to synthesize, model and fabricate a mechanical device subject to engineering constraints (e.g. cost and time/schedule)."

Subject:
Career and Technical Education
Technology and Engineering
Genetics
Chemistry
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Culpepper, Martin
Date Added:
01/01/2009
Engineering Nature: DNA Visualization and Manipulation
Read the Fine Print
Educational Use
Rating

Students are introduced to genetic techniques such as DNA electrophoresis and imaging ...

Students are introduced to genetic techniques such as DNA electrophoresis and imaging technologies used for molecular and DNA structure visualization. In the field of molecular biology and genetics, biomedical engineering plays an increasing role in the development of new medical treatments and discoveries. Engineering applications of nanotechnology such as lab-on-a-chip and deoxyribonucleic acid (DNA) microarrays are used to study the human genome and decode the complex interactions involved in genetic processes.

Subject:
Technology and Engineering
Life Science
Genetics
Physics
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
TeachEngineering.org
Date Added:
09/18/2014
Engineering Out of Harry Situations: The Science Behind Harry Potter
Read the Fine Print
Educational Use
Rating

Under the "The Science Behind Harry Potter" theme, a succession of diverse ...

Under the "The Science Behind Harry Potter" theme, a succession of diverse complex scientific topics are presented to students through direct immersive interaction. Student interest is piqued by the incorporation of popular culture into the classroom via a series of interactive, hands-on Harry Potter/movie-themed lessons and activities. They learn about the basics of acid/base chemistry (invisible ink), genetics and trait prediction (parseltongue trait in families), and force and projectile motion (motion of the thrown remembrall). In each lesson and activity, students are also made aware of the engineering connections to these fields of scientific study.

Subject:
Technology and Engineering
Life Science
Genetics
Mathematics
Chemistry
Physics
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Rachel Howser
TeachEngineering.org
Date Added:
09/18/2014
Evolving TCE Biodegraders
Read the Fine Print
Educational Use
Rating

A hypothetical scenario is introduced in which the class is asked to ...

A hypothetical scenario is introduced in which the class is asked to apply their understanding of the forces that drive natural selection to prepare a proposal along with an environmental consulting company to help clean up an area near their school that is contaminated with trichloroethylene (TCE). Students use the Avida-ED software application to test hypotheses for evolving (engineering) a strain of bacteria that can biodegrade TCE, resulting in a non-hazardous clean-up solution. Conduct this design challenge activity after completion of the introduction to digital evolution activity, Studying Evolution with Digital Organisms.

Subject:
Technology and Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering NGSS Aligned Resources
Author:
Amy Lark
Bio-Inspired Technology and Systems (BITS) RET,
Louise Mead
Robert Pennock
Wendy Johnson
Date Added:
09/18/2014
Experimental Microbial Genetics, Fall 2008
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating

" In this class, students engage in independent research projects to probe ...

" In this class, students engage in independent research projects to probe various aspects of the physiology of the bacteriumĺĘPseudomonas aeruginosa PA14, an opportunistic pathogen isolated from the lungs of cystic fibrosis patients. Students use molecular genetics to examine survival in stationary phase, antibiotic resistance, phase variation, toxin production, and secondary metabolite production. Projects aim to discover the molecular basis for these processes using both classical and cutting-edge techniques. These include plasmid manipulation, genetic complementation, mutagenesis, PCR, DNA sequencing, enzyme assays, and gene expression studies. Instruction and practice in written and oral communication are also emphasized. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented. Legal Notice "

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Croal, Laura
Laub, Michael
Melvold, Janis
Newman, Dianne
Date Added:
01/01/2008
A Family in Need: In-Class Case Study on Cancer Genetics
Read the Fine Print
Rating

“A Family in Need” was designed as an in-class problem-based learning activity ...

“A Family in Need” was designed as an in-class problem-based learning activity for students to learn about several innovative medical applications of molecular biology. Students assume the role of a second-year medical student assigned to work with a pediatric oncologist who has just biopsied a tumor-like growth in the adrenal gland of her 17-year-old patient, Lee F. After taking Lee’s family history and performing a pedigree analysis, students review clinical and genetic characteristics of several syndromes associated with adrenal cancer. Students then explore various diagnostic and biomedical research techniques such as PCR, DNA sequencing, and pre-implantation genetic diagnosis. The case concludes with a consideration of how to treat Lee’s condition with the help of gene cloning and the potential of gene therapy. Although originally written for an upper-level college genetics course, the case could also be adapted for an introductory molecular/cellular biology course, a non-majors biology course, or a professional school medical genetics course.

Subject:
Genetics
Material Type:
Case Study
Lecture Notes
Unit of Study
Provider:
National Center for Case Study Teaching in Science
Provider Set:
Case Study Collection
Date Added:
11/09/2017
The Fountain of Life: From Dolly to Customized Embryonic Stem Cells, Fall 2007
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating

" During development, the genetic content of each cell remains, with a ...

" During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimentally proven. Only 10 years ago the sheep Dolly was the first mammal to be cloned from an adult organism, demonstrating that the differentiated state of a mammalian cell can be fully reversible to a pluripotent embryonic state. A key conclusion from these experiments was that the difference between pluripotent cells such as embryonic stem (ES) cells and unipotent differentiated cells is solely a consequence of reversible changes. These changes, which have proved to involve reversible alterations to both DNA and to proteins that bind DNA, are known as epigenetic, to distinguish them from genetic alterations to DNA sequence. In this course we will explore such epigenetic changes and study different approaches that can return a differentiated cell to an embryonic state in a process referred to as epigenetic reprogramming, which will ultimately allow generation of patient-specific stem cells and application to regenerative therapy. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching."

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Meissner, Alexander
Date Added:
01/01/2007
Freshman Seminar: Structural Basis of Genetic Material: Nucleic Acids, Fall 2005
Conditional Remix & Share Permitted
CC BY-NC-SA
Rating

Since the discovery of the structure of the DNA double helix in ...

Since the discovery of the structure of the DNA double helix in 1953 by Watson and Crick, the information on detailed molecular structures of DNA and RNA, namely, the foundation of genetic material, has expanded rapidly. This discovery is the beginning of the "Big Bang" of molecular biology and biotechnology. In this seminar, students discuss, from a historical perspective and current developments, the importance of pursuing the detailed structural basis of genetic materials.

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Zhang, Shuguang
Date Added:
01/01/2005