Discover what controls how fast tiny molecular motors in our body pull through a single strand of DNA. How hard can the motor pull in a tug of war with the optical tweezers? Discover what helps it pull harder. Do all molecular motors behave the same?

Basic molecular structural principles of biological materials. Molecular structures of various materials of biological origin, including collagen, silk, bone, protein adhesives, GFP, self-assembling peptides. Molecular design of new biological materials for nanotechnology, biocomputing and regenerative medicine. Graduate students are expected to complete additional coursework. This course, intended for both graduate and upper level undergraduate students, will focus on understanding of the basic molecular structural principles of biological materials. It will address the molecular structures of various materials of biological origin, such as several types of collagen, silk, spider silk, wool, hair, bones, shells, protein adhesives, GFP, and self-assembling peptides. It will also address molecular design of new biological materials applying the molecular structural principles. The long-term goal of this course is to teach molecular design of new biological materials for a broad range of applications. A brief history of biological materials and its future perspective as well as its impact to the society will also be discussed. Several experts will be invited to give guest lectures.

This assignment uses a computer simulation of fruit fly genetics to have students design and interpret monohybrid crosses of a trait with simple dominant and recessive alleles. Detailed instructions with animated examples, background material, a sample report and a rubric are included.

This course focuses on the latest scientific developments and discoveries in the field of nanomechanics, the study of forces and motion on extremely tiny (10-9 m) areas of synthetic and biological materials and structures. At this level, mechanical properties are intimately related to chemistry, physics, and quantum mechanics. Most lectures will consist of a theoretical component that will then be compared to recent experimental data (case studies) in the literature. The course begins with a series of introductory lectures that describes the normal and lateral forces acting at the atomic scale. The following discussions include experimental techniques in high resolution force spectroscopy, atomistic aspects of adhesion, nanoindentation, molecular details of fracture, chemical force microscopy, elasticity of single macromolecular chains, intermolecular interactions in polymers, dynamic force spectroscopy, biomolecular bond strength measurements, and molecular motors.

Watch how NJ high school students apply basic principles of molecular biology to solve real research problems, and publish their own genome research at GenBank, the international genomic sequence database.

Subject assesses the relationships between sequence, structure, and function in complex biological networks as well as progress in realistic modeling of quantitative, comprehensive functional-genomics analyses. Topics include: algorithmic, statistical, database, and simulation approaches; and practical applications to biotechnology, drug discovery, and genetic engineering. Future opportunities and current limitations critically assessed. Problem sets and project emphasize creative, hands-on analyses using these concepts.

The discovery of restriction enzymes and their applications in DNA analysis has proven to be essential for biologists and chemists. This lesson focuses on restriction enzymes and their applications to DNA analysis and DNA fingerprinting. Use this lesson and its associated activity in conjunction with biology lessons on DNA analysis and DNA replication.

An active problem-based assignment that uses the Genbank database to teach the basics of molecular biology and molecular evolution

This is an interdisciplinary research project module with a 6-8 scope including NGSS (MS-LS4-5) and Common Core ELA standards (RST.6-8.1 and WHST.6-8.8) where learners explore Genetic Engineering and Gene Therapy uses and establish an evidence-based position to argue the question "Should humans harness genetic science and engineering for our benefit?"Expected sequence and timeframe for this module is approximately fifteen 60-minute periods in both science and ELA classrooms, which includes research time (with technology), composition of argumentative essays and Google Slides presentations.  Modifications for learners with exceptionalities are not included, but are readily accommodated through modifications to quantity of supports, DOK in delivery, and interpretation of the grading rubric(s). Resources include a Google Drive link that is able to be viewed by anyone with the link.  Please download the files or make a copy to your own Google Drive.

By this point in the unit, students have learned all the necessary information and conceptualized a design for how an optical biosensor could be used to detect a target strand of DNA associated with a cancer-causing gene as their solution to the unit's challenge question. Now student groups act as engineers again, using a poster format to communicate and prove the validity of the design. Successful posters include a description of refraction, explanations of refraction in a thin film, and the factors that can alter the interference pattern of a thin film. The posters culminate with an explanation of what is expected to be seen in a biosensing device of this type if it were coupled to a target molecule, proven with a specific example and illustrated with drawings and diagrams throughout. All the poster elements combine to prove the accuracy and viability of this method of gene detection. Together with its associated lesson, this activity functions as part of the summative assessment for this unit.

An interactive lecture that uses flash animations showing the researcher and their experiments that were used to develop the basic concepts in Mendelian genetics. Includes multiple choice questions students can answer in class.

In this video, we avoid telling the creatures what their survival chances are and let them figure it out themselves. This is the fifth in the series on evolution.

Snapshot Wisconsin is a partnership to monitor wildlife year-round, using a statewide network of trail cameras. Snapshot Wisconsin provides data needed for decision making at the Wisconsin Department of Natural Resources. It is also a unique opportunity for individuals, families, and students to get involved in monitoring the state’s valuable natural resources. This tool is designed to help visualize many aspects of Snapshot Wisconsin data.

" An opportunity for graduate study of advanced subjects in Brain and Cognitive Sciences not included in other subject listings. The key topics covered in this course are Bipolar Disorder, Psychosis, Schizophrenia, Genetics of Psychiatric Disorder, DISC1, Ca++ Signaling, Neurogenesis and Depression, Lithium and GSK3 Hypothesis, Behavioral Assays, CREB in Addiction and Depressive Behaviors, The GABA System-I, The GABA System-II, The Glutamate Hypothesis of Schizophrenia, The Dopamine Pathway and DARPP32."

Explore stretching just a single strand of DNA using optical tweezers or fluid flow. Experiment with the forces involved and measure the relationship between the stretched DNA length and the force required to keep it stretched. Is DNA more like a rope or like a spring?

Explore stretching just a single strand of DNA using optical tweezers or fluid flow. Experiment with the forces involved and measure the relationship between the stretched DNA length and the force required to keep it stretched. Is DNA more like a rope or like a spring?

Students observe natural selection in action and investigate the underlying mechanism, including random mutation and differential fitness based on environmental characteristics. They do this through use of the free AVIDA-ED digital evolution software application.

Students engineer and evolve digital organisms with the challenge to produce organisms with the highest fitness values in a particular environment. They do this through use of the free Avida-ED digital evolution software application. The resulting organisms compete against each other in the same environment and students learn the benefits of applying the principles of natural selection to solve engineering design problems.

This activity uses DNA sequences, protein sequence, and chromosome-density maps to re-trace the ancestry of humans and some of their closest relatives.