Students compare and contrast passive and active transport by playing a game to model this phenomenon. Movement through cell membranes is also modeled, as well as the structure and movement typical of the fluid mosaic model of the cell membrane. Concentration gradient, sizes, shapes and polarity of molecules determine the method of movement through cell membranes. This activity is associated with the Test your Mettle phase of the legacy cycle.

This online interactive website chalk full of games and simulations cover all of the following topics:
*Plasma membrane structure and function, roles of phospholipids, transport proteins (carrier and channel), cholesterol and carbohydrates, types of transport, diffusion, facilitated diffusion, active transport, osmosis. 

This is a perfect tutorial/game based/simulation driven online resource for teaching, re-teaching, or reviewing the basics behind the plasma membrane and cell transport.

Students learn about the different structures that comprise cell membranes, fulfilling part of the Research and Revise stages of the legacy cycle. They view online animations of cell membrane dynamics (links provided). Then they observe three teacher demonstrations that illustrate diffusion and osmosis concepts, as well as the effect of movement through a semi-permeable membrane using Lugol's solution.

This activity demonstrates diffusion, osmosis, and active transport through 12 interactive models. Start by following the path of a molecule of dye in water, create concentration gradients on either side of a cell membrane and watch the movement of substances in and out of a cell, and monitor the movement of oxygen into red blood cells with and without hemoglobin.

This lesson is an exploratory station activity to assist students in building a model of diffusion, as cellular transport.

Biological membranes are selectively permeable; some molecules can cross while others cannot. One way to affect this is through pore size. Change the pore size with the slider to change the permeability of the membrane to the different types of molecules. Trace an individual molecule to see the path it takes.

This course introduces the basic driving forces for electric current, fluid flow, and mass transport, plus their application to a variety of biological systems. Basic mathematical and engineering tools will be introduced, in the context of biology and physiology. Various electrokinetic phenomena are also considered as an example of coupled nature of chemical-electro-mechanical driving forces. Applications include transport in biological tissues and across membranes, manipulation of cells and biomolecules, and microfluidics.

Students are challenged to think as biomedical engineers and brainstorm ways to administer medication to a patient who is unable to swallow. They learn about the advantages and disadvantages of current drug delivery methods—oral, injection, topical, inhalation and suppository—and pharmaceutical design considerations, including toxicity, efficacy, size, solubility/bioavailability and drug release duration. They apply their prior knowledge about human anatomy, the circulatory system, polymers, crystals and stoichiometry to real-world biomedical applications. A Microsoft® PowerPoint® presentation and worksheets are provided. This lesson prepares students for the associated activity in which they create and test large-size drug encapsulation prototypes to provide the desired delayed release and duration timing.

Hands-on introduction to NMR presenting background in classical theory and instrumentation. Each lecture followed by lab experiments both to demonstrate ideas presented during the lecture and to familiarize students with state-of-the-art NMR instrumentation. Experiments cover topics ranging from spin dynamics to spectroscopy, and include imaging.

Unified treatment of phenomenological and atomistic kinetic processes in materials. Provides the foundation for the advanced understanding of processing, microstructural evolution, and behavior for a broad spectrum of materials. Emphasis on analysis and development of rigorous comprehension of fundamentals. Topics include: irreversible thermodynamics; diffusion; nucleation; phase transformations; fluid and heat transport; morphological instabilities; gas-solid, liquid-solid, and solid-solid reactions.

This course discusses the basics every manager needs to organize successful technology-driven innovation in both entrepreneurial and established firms. We start by examining innovation-based strategies as a source of competitive advantage and then examine how to build organizations that excel at identifying, building and commercializing technological innovations. Major topics include how the innovation process works; creating an organizational environment that rewards innovation and entrepreneurship; designing appropriate innovation processes (e.g. stage-gate, portfolio management); organizing to take advantage of internal and external sources of innovation; and structuring entrepreneurial and established organizations for effective innovation. The course examines how entrepreneurs can shape their firms so that they continuously build and commercialize valuable innovations. Many of the examples also focus on how established firms can become more entrepreneurial in their approach to innovation.

The goal of 3.044 is to teach cost-effective and sustainable production of solid material with a desired geometry, structure or distribution of structures, and production volume. Toward this end, it is organized around different types of phase transformations which determine the structure in various processes for making materials, in roughly increasing order of entropy change during those transformations: solid heat treatment, liquid-solid processing, fluid behavior, deformation processing, and vapor-solid processing. The course ends with several lectures that place the subject in the context of society at large.

Insert channels in a membrane and see what happens. See how different types of channels allow particles to move through the membrane.

Insert channels in a membrane and see what happens. See how different types of channels allow particles to move through the membrane.

Mathematical modeling of complex engineering systems at a level of detail compatible with the design and implementation of modern control systems. Wave-like and diffusive energy transmission systems. Multiport energy storing fields and dissipative fields; consequences of symmetry and asymmetry. Nonlinear mechanics and canonical transformation theory. Examples will include mechanisms, electromechanical transducers, electronic systems, fluid systems, thermal systems, compressible flow processes, chemical processes. This course models multi-domain engineering systems at a level of detail suitable for design and control system implementation. Topics include network representation, state-space models; multi-port energy storage and dissipation, Legendre transforms; nonlinear mechanics, transformation theory, Lagrangian and Hamiltonian forms; and control-relevant properties. Application examples may include electro-mechanical transducers, mechanisms, electronics, fluid and thermal systems, compressible flow, chemical processes, diffusion, and wave transmission.

Today, computer-based simulations are becoming increasingly popular, especially when daylighting and energy conservation are amongst the key goals for a project. This two-week workshop will expose participants to the current daylighting simulation models and beyond, by introducing realistic and dynamic assessment methods through hands-on exercises and application to a design project. Open to students and practitioners.

This course introduces the structure, composition, and physical processes governing the terrestrial planets, including their formation and basic orbital properties. Topics include plate tectonics, earthquakes, seismic waves, rheology, impact cratering, gravity and magnetic fields, heat flux, thermal structure, mantle convection, deep interiors, planetary magnetism, and core dynamics. Suitable for majors and non-majors seeking general background in geophysics and planetary structure.

"This course introduces the structure, composition, and physical processes governing the terrestrial planets, including their formation and basic orbital properties. Topics include plate tectonics, earthquakes, seismic waves, rheology, impact cratering, gravity and magnetic fields, heat flux, thermal structure, mantle convection, deep interiors, planetary magnetism, and core dynamics. Suitable for majors and non-majors seeking general background in geophysics and planetary structure."

This course is a project-based introduction to manipulating and characterizing cells and biological molecules using microfabricated tools. It is designed for first year undergraduate students. In the first half of the term, students perform laboratory exercises designed to introduce (1) the design, manufacture, and use of microfluidic channels, (2) techniques for sorting and manipulating cells and biomolecules, and (3) making quantitative measurements using optical detection and fluorescent labeling In the second half of the term, students work in small groups to design and test a microfluidic device to solve a real-world problem of their choosing. Includes exercises in written and oral communication and team building.

Principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Mass transport through membranes: diffusion, osmosis, chemically mediated, and active transport. Electric properties of cells: ion transport; equilibrium, resting, and action potentials. Kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the concepts. For juniors and seniors. Students engage in extensive written and oral communication exercises.