This research article provides the details of a current immunotherapy study performed by scientists at MIT. Immunotherapy is a relatively new and very promising cancer treatment that is now a focus of many cancer research labs. The article discusses what immunotherapy is, how T cell activation works, and how the treatment has eliminated some tumors in mice. As an interactive activity, students can practice making annotations in the margins of the article to check for understanding. Overall, students who read and dissect this article are learning how to comprehend complex biomedical research studies. As a supplemental activity, teachers can distribute the worksheet quiz posted in WISELearn. This set of questions (true/false, fill in the blank, multiple choice, short answer) assesses the students' comprehension levels of the current MIT immunotherapy research. An answer key is provided. The skills learned from investigating this article can hopefully be used to investigate other current biomedical research for human diseases and disorders.

Through two lessons and five activities, students explore the structure and function of cell membranes. Specific transport functions, including active and passive transport, are presented. In the legacy cycle tradition, students are motivated with a Grand Challenge question. As they study the ingress and egress of particles through membranes, students learn about quantum dots and biotechnology through the concept of intracellular engineering.

Tumor pathophysiology plays a central role in the growth, metastasis, detection, and treatment of solid tumors. Principles of transport phenomena are applied to develop a quantitative understanding of angiogenesis (formation of new blood vessels), blood flow and microcirculation, metabolism and microenvironment, transport and binding of small and large molecules, movement of cancer and immune cells, metastatic process, radiotherapy, chemotherapy, immunotherapy, hyperthermia, and photodynamic therapy of solid tumors.