The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.

Subject covers all major areas of cellular and molecular neurobiology including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell type determination, axon guidance and targeting, neuronal cell biology, synapse formation and plasticity. Includes lectures and exams, and involves presentation and discussion of primary literature. Focus on major concepts and recent advances in experimental neuroscience.

In this unit, students look at the components of cells and their functions and discover the controversy behind stem cell research. The first lesson focuses on the difference between prokaryotic and eukaryotic cells. In the second lesson, students learn about the basics of cellular respiration. They also learn about the application of cellular respiration to engineering and bioremediation. The third lesson continues students' education on cells in the human body and how (and why) engineers are involved in the research of stem cell behavior.

This course serves as an introduction to the structure and function of the nervous system. Emphasis is placed on the cellular properties of neurons and other excitable cells. Topics covered include the structure and biophysical properties of excitable cells, synaptic transmission, neurochemistry, neurodevelopment, and the integration of information in simple systems and the visual system.

Surveys the molecular and cellular mechanisms of neuronal communication. Covers ion channels in excitable membrane, synaptic transmission, and synaptic plasticity. Correlates the properties of ion channels and synaptic transmission with their physiological function such as learning and memory. Discusses the organizational principles for the formation of functional neural networks at synaptic and cellular levels.

Life as an emergent property of networks of chemical reactions involving proteins and nucleic acids. Mathematical theories of metabolism, gene regulation, signal transduction, chemotaxis, excitability, motility, mitosis, development, and immunity. Applications to directed molecular evolution, DNA computing, and metabolic and genetic engineering.

Covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation including molecular structure and assembly of MHC molecules, lymphocyte activation, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases. Consists of lectures and tutorials in which clinical cases are discussed with faculty tutors. Details of the case covering a number of immunological issues in the context of disease are posted on a student Web site.

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This activity engages learners in exploring the impact of climate change on arctic sea ice in the Bering Sea. They graph and analyze sea ice extent data, conduct a lab on thermal expansion of water, and then observe how a scientist collects long-term data on a bird population.

This is a course for those who are interested in the challenge posed by massive and persistent world poverty, and are hopeful that economists might have something useful to say about this challenge. The questions we will take up include: Is extreme poverty a thing of the past? What is economic life like when living under a dollar per day? Why do some countries grow fast and others fall further behind? Does growth help the poor? Are famines unavoidable? How can we end child labor - or should we? How do we make schools work for poor citizens? How do we deal with the disease burden? Is micro finance invaluable or overrated? Without property rights, is life destined to be "nasty, brutish and short"? Has globalization been good to the poor? Should we leave economic development to the market? Should we leave economic development to non-governmental organizations (NGOs)? Does foreign aid help or hinder? Where is the best place to intervene?

This class will focus on data analytics and professional practice in Geographic Information Systems. Students will participate in a collaborative data challenge project to engage with graduate students on a global-scale geospatial analysis problem. Penn State MGIS students will collaborate with graduate students from ITC - University of Twente located in Enschede, Netherlands to develop solutions to analyze spatio-temporal patterns in refugee migration data. Students will have the opportunity to present their work and develop new connections with EU geospatial professionals via site visits to European national mapping agencies. Students will work in teams to tackle this global-scale data set, and use geospatial analytics to arrive at a solution to visualize patterns over space and time.

This is an activity about solar flare activity. Learners will use whole-Sun maps of magnetic activity in order to identify possible future magnetic activity. They will take into account the rotation of the Sun and make day-to-day predictions of the overall Earth-side magnetic activity as suspected farside features rotate onto the Earth-side, and as Earth-side features rotate out of view onto the farside. Finally, learners will check the accuracy of their predictions. This activity requires access to the internet to obtain images from the Stanford University solar magnetic map archive from 1996 to 2011 and the GOES X-ray image archive. This is Activity 9 of the Space Weather Forecast curriculum.

This course aims to connect the principles, concepts, and laws/postulates of classical and statistical thermodynamics to applications that require quantitative knowledge of thermodynamic properties from a macroscopic to a molecular level. It covers their basic postulates of classical thermodynamics and their application to transient open and closed systems, criteria of stability and equilibria, as well as constitutive property models of pure materials and mixtures emphasizing molecular-level effects using the formalism of statistical mechanics. Phase and chemical equilibria of multicomponent systems are covered. Applications are emphasized through extensive problem work relating to practical cases.

Laboratory or field work in atmospheric science and oceanography. To be arranged with department faculty. Consult with department Education Office. This is an undergraduate introductory laboratory subject in ocean chemistry and measurement. There are three main elements to the course: oceanic chemical sampling and analysis, instrumentation development for the ocean environment, and the larger field of ocean science. This course is offered as part of the MIT/WHOI Joint Program in Oceanography/Applied Ocean Science and Engineering.

Introduction to the fundamental principles of chemistry including atomic structure, stoichiometry, the periodic table of the elements, chemical bonding, molecular structure, and states of matter based on kinetic theory. This course is intended for majors in any of the sciences, including pre-dental, pre-medical, and pre-engineering students

This course is designed to prepare students for the challenges that face the chemist in modern society.

Introduces the design of chemical reactors via synthesis of chemical kinetics, transport phenomena, and mass and energy balances. Topics: reaction mechanisms and chemical/biochemical pathways; transition-state theory; batch, plug flow and well-stirred reactors; heterogeneous and enzymatic catalysis; heat and mass transport in reactors, including diffusion to and within catalyst particles and cells or immobilized enzymes.

For Institute students in all departments interested in the behavior of chemicals in the environment (see ESD listings for other subjects). Emphasis on man-made chemicals, their movement through water, air, soil, and their eventual fate. Physical transport, as well as chemical and biological sources and sinks, are discussed. Linkages to health effects, sources and control, and policy aspects.

This course addresses the challenges of defining a relationship between exposure to environmental chemicals and human disease. Course topics include epidemiological approaches to understanding disease causation; biostatistical methods; evaluation of human exposure to chemicals, and their internal distribution, metabolism, reactions with cellular components, and biological effects; and qualitative and quantitative health risk assessment methods used in the U.S. as bases for regulatory decision-making. Throughout the term, students consider case studies of local and national interest.