In this course problems from biological engineering are used to develop structured computer programming skills and explore the theory and practice of complex systems design and construction.

"This course covers the principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. Mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Tissue and organ regeneration. Design of implants and prostheses based on control of biomaterials-tissue interactions. Comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Criteria for restoration of physiological function for tissues and organs."

Analyzes computational needs of clinical medicine reviews systems and approaches that have been used to support those needs, and the relationship between clinical data and gene and protein measurements. Topics: the nature of clinical data; architecture and design of healthcare information systems; privacy and security issues; medical expertsystems; introduction to bioinformatics. Case studies and guest lectures describe contemporary systems and research projects. Term project using large clinical and genomic data sets integrates classroom topics.

This course provides intensive coverage of the theory and practice of electromechanical instrument design with application to biomedical devices. Students will work with MGH doctors to develop new medical products from concept to prototype development and testing. Lectures will present techniques for designing electronic circuits as part of complete sensor systems. Topics covered include: basic electronics circuits, principles of accuracy, op amp circuits, analog signal conditioning, power supplies, microprocessors, wireless communications, sensors, and sensor interface circuits. Labs will cover practical printed circuit board (PCB) design including component selection, PCB layout, assembly, and planning and budgeting for large projects. Problem sets and labs in the first six weeks are in support of the project. Major team-based design, build, and test project in the last six weeks. Student teams will be composed of both electrical engineering and mechanical engineering students.

Seminars exploring current research and topical issues in the biomedical sciences, addressed at the general theme of innovation. Seminars are organized in blocks with related content, and are presented by prominent outside speakers as well as by HST faculty members and graduate students. Each seminar block includes several semi-weekly presentations, in addition to wide-ranging discussions among speakers, faculty, and students. Discussions involve issues such as relations between presented research areas, requirements for further advances in the "state of the art", the role of enabling technologies, the responsible practice of biomedical research, and career paths in the biomedical sciences. This course consists of a series of seminars focused on the development of professional skills. Each semester focuses on a different topic, resulting in a repeating cycle that covers medical ethics, responsible conduct of research, written and oral technical communication, and translational issues. Material and activities include guest lectures, case studies, interactive small group discussions, and role-playing simulations.

Seminars exploring current research and topical issues in the biomedical sciences, addressed at the general theme of innovation. Seminars are organized in blocks with related content, and are presented by prominent outside speakers as well as by HST faculty members and graduate students. Each seminar block includes several semi-weekly presentations, in addition to wide-ranging discussions among speakers, faculty, and students. Discussions involve issues such as relations between presented research areas, requirements for further advances in the "state of the art", the role of enabling technologies, the responsible practice of biomedical research, and career paths in the biomedical sciences.

" This course teaches the design of contemporary information systems for biological and medical data. Examples are chosen from biology and medicine to illustrate complete life cycle information systems, beginning with data acquisition, following to data storage and finally to retrieval and analysis. Design of appropriate databases, client-server strategies, data interchange protocols, and computational modeling architectures. Students are expected to have some familiarity with scientific application software and a basic understanding of at least one contemporary programming language (e.g. C, C++, Java, Lisp, Perl, Python). A major term project is required of all students. This subject is open to motivated seniors having a strong interest in biomedical engineering and information system design with the ability to carry out a significant independent project. This course was offered as part of the Singapore-MIT Alliance (SMA) program as course number SMA 5304."

This course presents the fundamentals of digital signal processing with particular emphasis on problems in biomedical research and clinical medicine. It covers principles and algorithms for processing both deterministic and random signals. Topics include data acquisition, imaging, filtering, coding, feature extraction, and modeling. The focus of the course is a series of labs that provide practical experience in processing physiological data, with examples from cardiology, speech processing, and medical imaging. The labs are done on the MIT Server in MATLABĺ¨ during weekly lab sessions that take place in an electronic classroom. Lectures cover signal processing topics relevant to the lab exercises, as well as background on the biological signals processed in the labs.

This subject deals primarily with kinetic and equilibrium mathematical models of biomolecular interactions, as well as the application of these quantitative analyses to biological problems across a wide range of levels of organization, from individual molecular interactions to populations of cells.

" BLOSSOMS stands for Blended Learning Science or Math Studies. It is a project sponsored by MIT LINC (Learning International Networks Consortium) a consortium of educators from around the world who are interested in using distance and e-Learning technologies to help their respective countries increase access to quality education for a larger percentage of the population.BLOSSOMS Online"

An advanced course covering anatomical, physiological, behavioral, and computational studies of the central nervous system relevant to speech and hearing. Students learn primarily by discussions of scientific papers on topics of current interest. Recent topics include cell types and neural circuits in the auditory brainstem, organization and processing in the auditory cortex, auditory reflexes and descending systems, functional imaging of the human auditory system, quantitative methods for relating neural responses to behavior, speech motor control, cortical representation of language, and auditory learning in songbirds.

This course provides an outline of vertebrate functional neuroanatomy, aided by studies of comparative neuroanatomy and evolution, and by studies of brain development. Topics include early steps to a central nervous system, basic patterns of brain and spinal cord connections, regional development and differentiation, regeneration, motor and sensory pathways and structures, systems underlying motivations, innate action patterns, formation of habits, and various cognitive functions. In addition, lab techniques are reviewed and students perform brain dissections.

Survey of principles underlying the structure and function of the nervous system, integrating molecular, cellular, and systems approaches. Topics: development of the nervous system and its connections, cell biology or neurons, neurotransmitters and synaptic transmission, sensory systems of the brain, the neuroendocrine system, the motor system, higher cortical functions, behavioral and cellular analyses of learning and memory. First half of an intensive two-term survey of brain and behavioral studies for first-year graduate students. Open to graduate students in other departments, with permission of instructor.

This class is the second half of an intensive survey of cognitive science for first-year graduate students. Topics include visual perception, language, memory, cognitive architecture, learning, reasoning, decision-making, and cognitive development. Topics covered are from behavioral, computational, and neural perspectives.

There are several hundred thousand Brownfield sites across the country. The large number of sites, combined with how a majority of these properties are located in urban and historically underserved communities, dictate that redevelopment of these sites stands to be a common theme in urban planning for the foreseeable future. Students form a grounded understanding of the Brownfield lifecycle: how and why they were created, their potential role in community revitalization, and the general processes governing their redevelopment. Using case studies and guest speakers from the public, private and non-profit sectors, students develop and hone skills to effectively address the problems posed by these inactive sites.

Are you interested in building and testing your own imaging radar system? MIT Lincoln Laboratory offers this 3-week course in the design, fabrication, and test of a laptop-based radar sensor capable of measuring Doppler, range, and forming synthetic aperture radar (SAR) images. You do not have to be a radar engineer but it helps if you are interested in any of the following; electronics, amateur radio, physics, or electromagnetics. It is recommended that you have some familiarity with MATLAB;. Teams of three students will receive a radar kit and will attend a total of 5 sessions spanning topics from the fundamentals of radar to SAR imaging. Experiments will be performed each week as the radar kit is implemented. You will bring your radar kit into the field and perform additional experiments such as measuring the speed of passing cars or plotting the range of moving targets. A final SAR imaging contest will test your ability to form a SAR image of a target scene of your choice from around campus; the most detailed and most creative image wins.

" This course covers examination of the state of knowledge of planetary formation, beginning with planetary nebulas and continuing through accretion (from gas, to dust, to planetesimals, to planetary embryos, to planets). It also includes processes of planetary differentiation, crust formation, atmospheric degassing, and surface water condensation. This course has integrated discussions of compositional and physical processes, based upon observations from our solar system and from exoplanets. Focus on terrestrial (rocky and metallic) planets, though more volatile-rich bodies are also examined."

This course will serve as a two-week aggressively gentle introduction to programming for those students who lack background in the field. Specifically targeted at students with little or no programming experience, the course seeks to reach students who intend to take 6.001 in the Spring Term and feel they would struggle because they lack the necessary background. The main focus of the subject will be acquiring programming experience: instruction in programming fundamentals coupled with lots of practice problems. Lots of programming required, but lots of support provided.

This course addresses advanced topics in structures, exterior envelopes and contemporary production technologies. It continues the exploration of structural elements and systems; expanding to include more complex determinant, indeterminate, long-span and high-rise systems. Some of the topics covered include reinforced concrete, steel and engineered wood design, and an introduction to tensile systems. The contemporary exterior envelope is discussed with an emphasis on the classification of systems, their performance attributes and advanced manufacturing technologies.

This course addresses advanced structures, exterior envelopes and contemporary production technologies. It continues the exploration of structural elements and systems, and expands to include more complex determinante, indeterminate, long-span and high-rise systems. It covers topics such as reinforced concrete, steel and engineered wood design, and provides an introduction to tensile systems. Lectures also address the contemporary exterior envelope with an emphasis on their performance attributes and advanced manufacturing technologies.