As the severity of the AIDS epidemic increased during the mid-1980s, the inadequacy of AIDS education and treatment came under assault from activists, many of whom were themselves infected with the disease. Michael Yantsos, who became infected with AIDS in prison in 1983, was one of those who spoke out when conditions at Rikers Island Prison Hospital in New York City became unbearable. In 1986, as prisoners were dying at the rate of one every two weeks from AIDS, Yantsos and his fellow inmates went on hunger strike to publicize the unsanitary conditions in the prison's AIDS ward, which included leaks, rodents, insects, and inadequate food and medical attention. The prisoners' efforts succeeding in publicizing the issue and winning some reforms in the ward's conditions.

Before the general public began to understand the health dangers of sunlight overexposure, a fair number of white Americans devoted much time and effort to acquiring a "perfect tan." The suntan craze began in the mid-1920s, as outdoor recreation became more popular among middle-class Americans. Marketers also promoted the practice--once convinced that suntanning was not just a fad--with products designed to assist the quest to be tan. The following 1949 editorial from the popular magazine Collier's offers a tongue-in-cheek critique of tanning, calling attention to peer group pressures of social conformity and competitiveness inherent in tanning rituals. Absent from the piece is any consideration of the racial aspects of such a practice, centered on darkening the color of one's skin, and performed, as it was, in a multiethnic, but white-dominated society.

The availability of rail connections often determined whether a western community would survive or die. The rails fostered prosperity by bringing both goods and people. This trade, and the local service industries that sprouted up to capitalize on the movement of people and goods, drove many local economies. Here, David Hickman talked about the boom years that followed the arrival of the railroad in the Latah County, Idaho town of Genesee in the 1880s.

All of us have felt sick at some point in our lives. Many times, we find ourselves asking, "What is the quickest way that I can start to feel better?" During this two-lesson unit, students study that question and determine which form of medicine delivery (pill, liquid, injection/shot) offers the fastest relief. This challenge question serves as a real-world context for learning all about flow rates. Students study how long various prescription methods take to introduce chemicals into our blood streams, as well as use flow rate to determine how increasing a person's heart rate can theoretically make medicines work more quickly. Students are introduced to engineering devices that simulate what occurs during the distribution of antibiotic cells in the body.

First aid is the provision of immediate care to a victim with an injury of illness, usually effected by a lay person, and performed within a limited skill range. First aid is normally performed until the injury or illness is satisfactorily dealt with (such as in the case of small cuts, minor bruises, and blisters) or until the next level of care, such as an ambulance or doctor, arrives. This book is a Canadian version of the original at Wikibooks. All references to protocols which do not comply with resuscitation standards in Canada have been removed.

Frenchman Louis Daguerre's improvements in photography reached America in the 1840s. Personal portraits were soon the craze, and daguerreotype' studios sprang up in every city, while traveling daguerreotypists served the countryside. This picture presents the controlled environment of the early studios. It took so long to properly expose a photographic plate that the subject needed a head brace to hold a pose.

Relatively few Americans directly experienced trench warfare and poison gas, innovations that rendered war newly terrible and fearsome. One such participant was William L. Langer, later a historian of the war, Harvard professor, and president of the American Historical Association. Langer served as an engineer in Company E of the 1st Gas Regiment, Chemical Warfare Service, of the U.S. Army. In this taut account, from Gas and Flame in World War I, he described a harrowing mission to move supplies and munitions near enemy lines, in preparation for a machine gun and gas attack. Langer noted that his story was probably the first published by an American unit after the war; four hundred copies were printed for the members of the 1st Gas Regiment.

The penetration of the railroads into the West in the late nineteenth century had a profound impact on local economies. For a period of ten years in the 1880s the Latah County, Idaho town of Genesee experienced this phenomenon. One town boomed while its neighbors languished in economic isolation, largely as a result of the rail station in Genesee. In this oral history interview, Kenneth Platt described the railroad's impact on Latah County.

GEM4 VisionGEM4 has brought together researchers and professionals in major institutions across the globe with distinctly different, but complementary, expertise and facilities to address significant problems at the intersections of select topics of engineering, life sciences, technology, medicine and public health.GEM4 creates new models for interactions across scientific disciplinary boundaries whereby problems spanning the range of fundamental science to clinical studies and public health can be addressed on a global scale through strategic international partnerships.Through initial focus areas in cell and molecular biomechanics, and environmental health, in the context of select human diseases, GEM4 creates a global forum for the definition and exploration of grand challenges and scientific studies, for the cross-fertilization of ideas among engineers, life scientists and medical professionals, and for the development of novel educational tools.GEM4 ActivitiesGEM4 enables the brokering of engineers, life scientists and medical professionals with shared facilities and joint students and post-doctoral fellows to tackle major problems in the context of human health and diseases that call for state-of-the-art experimental and computational tools in cell and molecular mechanics, biology and medicine. Broad examples of problems addressed include:infectious diseases such as malaria,cancer,cardiovascular diseases,biomechanical origins of inflammation.In each of these areas, the initial emphasis has included (but will not be limited to) molecular, subcellular and cellular mechanics applied to biomedicine, where a single investigator or institution is not likely to have the full spectrum of expertise, infrastructure or resources available to cover fundamental molecular science all the way to clinical studies and societal implications. Currently, twelve institutions in North America, Europe and Asia participate in this effort as Core institutions, focusing on mechanistic studies, as well as novel methods for diagnostics, vaccines or drug development and delivery.Funds have been raised to provide a structure for coordinated studies from major organizations under the umbrella of GEM4. These funds are being used for:organization of major symposia/conferences specifically targeted at the theme areas of the initiative,training grants for student fellowships for the partner institutions,summer schools to develop teaching materials,the exchange of students and researchers,operations of a central secretariat for handling the administrative and infrastructure details for such interactions,maintenance of a web site for dissemination of information.

The quest for efficiency touched nearly every aspect of American life during World War I, including the nation's clocks. Daylight saving first appeared during the war years as an experiment to save fuel. Theoretically, people would use less artificial light in the evenings thanks to the extra hour of daylight. Urban dwellers generally delighted in the "extra hour," but protests by farmers and other rural citizens brought the experiment to an end after only one year. Farmers, rural Americans, and those whose jobs forced them to work very early hours disliked the measure intensely. They bombarded Congress with petitions, letters, and angry telegrams demanding the return to "God's time." According to farmers, city dwellers who wanted more leisure in the afternoon could just show up for work an hour earlier and leave an hour earlier.

For four years after the U.S. dropped atom bombs on Hiroshima and Nagasaki to end World War II, America held a monopoly on the production of atomic weapons. On September 24, 1949, however, news of a Soviet Union nuclear weapons test shocked the nation. The following April, a National Security Council report to President Harry S. Truman advised development of a hydrogen bomb--some 1,000 times more destructive than an atom bomb--and a massive buildup of non-nuclear defenses. The subsequent outbreak of war in Korea in June 1950 justified to many increased defense spending. When fighting reached a stalemate, some in politics and the military--including General Douglas MacArthur, head of the Far East command--advocated the use of atomic weapons against targets in China. Although the Korean War was fought solely with conventional weapons, peace came only after the Eisenhower administration threatened to use nuclear weapons. Following the July 1953 armistice, government and military officials debated the place of nuclear weapons in future defense planning. In this January 1954 Collier's article, Styles Bridges, chairman of the Senate Appropriations Committee, laid out various proposals and assured citizens of their leaders' dedication "to finding the best solution." Despite a test ban treaty in 1963--sparked in part by the 1962 Cuban Missile Crisis that brought the U.S. and the Soviet Union to the brink of nuclear war--subsequent arms control agreements, and a vigorous nuclear freeze movement, the two superpowers nevertheless pursued an escalating arms race that reached a peak combined total of nearly 60,000 nuclear warheads by the late 1980s.

Silicosis, a deadly lung disease caused when workers inhale fine particles of silica dust (found in sand, quartz, and granite), became a national cause clbre during the Great Depression when it was recognized as a significant disease among lead, zinc, and silver miners, sandblasters, and foundry and tunnel workers. While silicosis was a crisis for the federal government, business, and insurance companies as well as labor organizations, its most devastating effects were on the workers who contracted the disease and the families and communities who watched previously healthy men waste away and die. The lasting impact that the silicosis "plague" had on individual workers' lives in the 1930s is evident here in Laurie Mercier's 1981 interview with Helen Raymond, who opened a tavern that catered to miners in Virginia City, Montana, in 1934.

In 1918 and 1919, the Spanish influenza killed 550,000 people in the United States and 20 to 40 million worldwide. In a 1982 interview with Laurie Mercier, Loretta Jarussi of Bearcreek, Montana, described how people would pass through that tiny town seemingly healthy, only to be reported dead two days later. Her father went undiagnosed for many weeks and had plans to go to a nearby hot springs to rest. She believed that her father's death was averted only because the son of the local doctor was an army doctor who recognized flu symptoms that others missed.

Examines the development of computing techniques and technology in the nineteenth and twentieth centuries, particularly critical evaluation of how the very idea of "computer" changes and evolves over time. Emphasis is on technical innovation, industrial development, social context, and the role of government. Topics include Babbage, Hollerith, differential analyzers, control systems, ENIAC, radar, operations research, computers as scientific instruments, the rise of "computer science," artificial intelligence, personal computers, and networks. Includes class visits by members of the MIT community who have made important historical contributions. This course focuses on one particular aspect of the history of computing: the use of the computer as a scientific instrument. The electronic digital computer was invented to do science, and its applications range from physics to mathematics to biology to the humanities. What has been the impact of computing on the practice of science? Is the computer different from other scientific instruments? Is computer simulation a valid form of scientific experiment? Can computer models be viewed as surrogate theories? How does the computer change the way scientists approach the notions of proof, expertise, and discovery? No comprehensive history of scientific computing has yet been written. This seminar examines scientific articles, participants' memoirs, and works by historians, sociologists, and anthropologists of science to provide multiple perspectives on the use of computers in diverse fields of physical, biological, and social sciences and the humanities. We explore how the computer transformed scientific practice, and how the culture of computing was influenced, in turn, by scientific applications.

Students are introduced to a challenge question. Towards answering the question, they generate ideas for what they need to know about medicines and how they move through our bodies, watch a few short videos to gain multiple perspectives, and then learn lecture material to obtain a basic understanding of how antibiotics kill bacteria in the human body. They learn why different forms of medicine (pill, liquid or shot) get into the blood stream at different speeds.

When AIDS struck the gay community during the early 1980's, many who had not previously consider themselves activists, like Bruce Priebe, became politically active. Militancy, political action, and demands for rights and recognition within the gay and lesbian community had been building throughout the post-war period. While many homosexual men and women first expressed their sexuality during World War II, a period of relative, albeit silent, tolerance, the movement for gay rights became more assertive following the 1969 Stonewall Riot, when New York City police raided a gay club. The burst of community health activism in response to the AIDS epidemic built on these earlier expressions of "gay pride" and activism.

In the early 20th century, new household technology was both accomplished and inspired by the tremendous increase in American industrial production. As in industry, mechanization and scientific management were part of a larger reorganization of work. And as in industry, efficient housekeeping was partially a response to labor unrest--both the "servant problem" and the growing disquiet of middle-class wives. Machines offered salvation through technology; scientific housework promised satisfaction through systematic and efficient methods. But middle-class wives themselves voiced a discontent that could not be addressed through new purchases or better systems. In 1923, Woman's Home Companion solicited readers' letters for a series that offered the magazine as a clearinghouse for women's household problems and solutions. In response, nearly two thousand women wrote letters to the magazine. Skeptical of the solutions afforded by washing machines and efficiency methods, many of them called for cooperative housekeeping, paid work, help from children and husbands, and equality in marriage--solutions not contemplated by the enthusiasts of either scientific housekeeping or the new household technology.

Born in Forreston, Illinois, in 1868, Sylvie Thygeson taught and worked as a stenographer and typist before her marriage at the age of twenty-three. She and her husband, a lawyer, lived in St. Paul, Minnesota. An activist for women's rights, including suffrage and the legalization of contraception, Thygeson felt that birth control was both a crucial part of egalitarian marriage and a major political commitment. In this interview, conducted in 1972 by her daughter Mary Thygeson Shepardson and historian Sherna Gluck, Thygeson described her and her husband's decision to limit their family, a choice that enabled her to work in the suffrage and birth control movements. Her account offered an intriguing glimpse of how birth control advocates circulated information about contraception at a time when many physicians refused to do so, and when both law and public opinion constrained such practices.

Students continue the research begun in the associated lesson as if they were biomedical engineers working for a pharmaceutical company. Groups each perform a simple chemical reaction (to precipitate solid calcium out of solution) to observe what may occur when Osteopontin levels drop in the body. With this additional research, students determine potential health complications that might arise from a new drug that could reduce inflammatory pain in many patients, improving their quality of life. The goal of this activity is to illustrate biomedical engineering as medical problem solving, as well as emphasize the importance of maintaining normal body chemistry.

On July 1, 1946, less than a year after dropping atom bombs on Hiroshima and Nagasaki to end World War II, the U.S. embarked on its first postwar atomic weapons test at the Bikini Atoll in the Marshall Islands. David Bradley, a physician and member of the Radiological Safety Unit at Bikini, voiced concern over dangers from radioactivity in his 1948 best-seller, No Place to Hide. In response to Bradley and other critics, the Atomic Energy Commission, the military, and other government agencies attempted to diffuse growing fears about radioactivity. The following Collier's article by a military officer--using the same eyewitness-account format as in Bradley's book--tried to persuade its readers that fears about "lingering radiation" were unfounded by documenting a test in the Nevada desert in which the military deliberately sent soldiers close to "ground zero" soon after an explosion. Some readers remained unconvinced; their published letters can be found following the article. In 1963, the U.S. and Soviet Union signed a treaty to halt atmospheric tests of nuclear weapons. By that time, some 300,000 U.S. military personnel and an unknown number of civilians in areas downwind from the test sites had been exposed to radiation. In subsequent years, studies revealed higher rates of leukemia, cancer, respiratory ailments, and other health problems among these groups. Underground atomic weapons tests continued at the Nevada Test Site until a moratorium was declared in 1992, after 928 nuclear tests.